2,5-Di-tert-butylhydroquinone

Overview

2,5-Di-tert-butylhydroquinone (BHQ) (Compound 2), an indirect food additive, is a Sarco/endoplasmic reticulum Ca 2+ ATPase (SERCA) inhibitor with an IC 50 of 400 nM. 2,5-Di-tert-butylhydroquinone disrupts the gating function of the residue Glu309 which prevents Ca 2+ from reaching their binding site. 2,5-Di-tert-butylhydroquinone regulates the activity of 5-lipoxygenase and COX-2 ( IC 50 : 1.8 and 14.1 μM for 5-LO and COX-2 , respectively).

Application

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Product Information

• Catalog No.: HY-W012399
• CAS No.: 88-58-4
• Molecular Formula: C14H22O2
• Molecular Weight: 222.33
• Purity: 99.73%
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (11.24 mM); Clear solution
• Availability: In-stock

Source

Original product source