LY83583 is inhibitor of soluble guanylate cyclase ( sGC ) with the ability to target the cGMP signaling pathway. LY83583 inhibits the kinase activity-related proliferation of tumor cells by inducing the Cdk inhibitor p21 . LY83583 can be used for the study of cancers (colorectal cancer , breast cancer and melanoma) and cardiovascular disease .
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