(E/Z)-Locostatin

Overview

(E/Z)-Locostatin ((E/Z)-UIC-1005) is a racemic of Locostatin. Locostatin (UIC-1005) is a potent RKIP inhibitor. Locostatin binds Raf kinase inhibitor RKIP protein and disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. Locostatin inhibits cell proliferation and migration. Locostatin aggravates thioacetamide ( HY-Y0698 )-induced acute liver failure in mice .

Application

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Product Information

• Catalog No.: HY-W013411
• CAS No.: 133812-16-5
• Molecular Formula: C14H15NO3
• Molecular Weight: 245.27
• Purity: 99.52%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (10.19 mM); Clear solution
• Availability: In-stock

Source

Original product source