Inosine-5'-diphosphate disodium

Overview

Inosine-5'-diphosphate disodium (IDP disodium) is a decoy substrate of NM23-H2 . Inosine-5'-diphosphate disodium has a superior bond capacity on GDP-binding pocket of NM23-H2 ( K D : 5.0 μM). Inosine-5'-diphosphate disodium abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate disodium has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate disodium can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research.

Application

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Product Information

• Catalog No.: HY-W013724
• CAS No.: 54735-61-4
• Molecular Formula: C10H14N4O11P2
• Molecular Weight: 428.19
• Purity: 99.08%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source