2,4′-Dihydroxybenzophenone

2,4′-Dihydroxybenzophenone
  • CAS No.:131-56-6
  • Grade:98.00%
  • Formula:C13H10O3
  • M.W.:214.22
  • Solvent:≥ 5 mg/mL (23.34 mM); Clear solution

Overview

2,4′-Dihydroxybenzophenone (Ultraviolet absorber UV-0) occupies the hydrophobic pocket of MD2 and blocks the dimerization of TLR4 . 2,4′-Dihydroxybenzophenone inhibits the LPS induced mtROS production, and LPS induced inflammatory response by downregulating pro-inflammatory mediators and decreasing the expression of MyD88 , p-IRAK4, and NF-κB . 2,4′-Dihydroxybenzophenone is also a UV absorber.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Obesity | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > MyD88 | Products > Signaling Pathways > Environmental Pollutants | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > IRAK

Product Information

  • Catalog No.: HY-W014223
  • CAS No.: 131-56-6
  • Molecular Formula: C13H10O3
  • Molecular Weight: 214.22
  • Purity: 98.00%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 5 mg/mL (23.34 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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