L-2-Hydroxyglutaric acid disodium

Overview

L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer . L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase ( Mi-CK ) activity with K m and K i of 2.52 mM and 11.13 mM, respectively.

Application

Products | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Histone Demethylase | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-W015114
• CAS No.: 63512-50-5
• Molecular Formula: C5H6Na2O5
• Molecular Weight: 192.08
• Purity: 99.76%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 25 mg/mL (130.15 mM); Clear solution; Need ultrasonic and warming
• Availability: In-stock

Source

Original product source