PD-166793

Overview

PD-166793 is a potent, selective, orally active and wide-broad spectrum inhibitor of MMP , exhibiting nanomolar potency against MMP-2 , MMP-3 and MMP-13 ( IC 50 =4, 7, and 8 nM, respectively) and micromolar potency vs MMP-1 , -7 and -9 ( IC 50 =6.0, 7.2, and 7.9 μM, respectively). PD-166793 can attenuate left ventricular remodeling and dysfunction in a rat model of progressive heart failure.

Application

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Product Information

• Catalog No.: HY-107428
• CAS No.: 199850-67-4
• Molecular Formula: C17H18BrNO4S
• Molecular Weight: 412.30
• Purity: 99.21%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.06 mM); Clear solution
• Availability: In-stock

Source

Original product source