Benzanthrone

Overview

Benzanthrone is an immunotoxic, pro-inflammatory Photosensitizer . Benzanthrone upregulates iNOS , COX-2 and inflammatory cytokines; activates ERK1/2 , p38 , JNK , AP-1 and NF-κB ; inhibits Nrf2 ; and induces oxidative stress and DNA damage. Upon radiation exposure, Benzanthrone generates singlet oxygen and superoxide anion radicals, induces photohemolysis and lipid peroxidation, and alters the levels of skin xenobiotic enzymes . Benzanthrone exhibits differential genotoxicity in different cell lines. Benzanthrone possesses skin tumor-initiating and promoting activities. Benzanthrone can be used in skin tumor-related studies.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Melanoma | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > COX | Products > Signaling Pathways > ERK | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > JNK | Products > Signaling Pathways > AP-1 | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Photosensitizer | Products > Signaling Pathways > NO Synthase

Product Information

• Catalog No.: HY-W026930
• CAS No.: 82-05-3
• Molecular Formula: C17H10O
• Molecular Weight: 230.26
• Purity: 99.69%
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source